Name : Morteza
Family :Sanei Taheri
Affiliation : Radiology Department,Shohada Tajrish Hospital,SBMU
Academic Degree: Associate Professor of Radiology
Resident : Hussein Soleiman Tabar
Gender : Female
Age : 40
40-year-old female, clinical history withheld
Imaging Procedures and Findings
Plain radiographs reveal widespread amorphous soft tissue calcification.
Progressive systemic sclerosis (Scleroderma), a condition with unknown etiology, causes small vessel disease and fibrosis in several organs. Scleroderma is the cutaneous manifestation of the disease. It often presents with Raynaud's phenomenon and skin changes. Typical features are terminal phalangeal resorption (acro-osteolysis) due to pressure atrophy, discrete dense plaques of calcification (calcinosis circumscripta) and occasional intra-articular calcification. Erosive changes can occur which may be due to concurrent rheumatoid arthritis or some form of overlapping condition. The related CREST syndrome is due to the combination of calcinosis, Raynaud's phenomenon, oesophageal dysmotility, scleroderma and telangiectasia. The calcification may also involve the tendon sheaths.
Progressive systemic sclerosis
Adam A, Dixon AK: Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging, 5th ed. Philadelphia: Elsevier Churchill Livingstone, 2008.